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Cell (2014) 157:151526

Helps improve skin elasticity and firmness

These unit costs were used to calculate annual costs of treatment for each arm, based on the resource use from the PIONEER 2 and 3 clinical trials for comparisons with empagliflozin and dulaglutide, respectively

The 24% average weight loss at 48 weeks approaches what bariatric surgery achieves, and the metabolic improvements extend far beyond the scale

Nevertheless, this study contributes to the overall understanding of canagliflozins safety profile and supports the need for further investigations into its potential neuroprotective effects using more specific neuropathy endpoints [25]